
Basophils are a type of white blood cell. These cells normally constitute 0.01 to 0.3% of the circulating white blood cells. These cells contain compounds which the immune system utilizes when it responds to an infection or inflammation. They circulate throughout the body in the blood stream, with the ability to pass into various tissues as needed. When an infectious agent is detected by the immune system, basophils respond, along with numerous other types of white blood cells.
They are also involved in inflammatory reactions in the body, especially those related to allergies and asthma. When stimulated, basophils release histamine and other enzymes that can lead to inflammation, bronchoconstriction, and asthma symptoms.