Mixing an acai berry drink with alcohol does not have any reported harmful impact. In fact, research has shown that mixing antioxidant berries with alcohol can actually increase their antioxidant properties. However, it makes little sense to increase your alcohol intake when you are taking the acai berry drink. This is because the drink is mainly used to detoxify and cleanse your system. By drinking alcohol, you are merely replacing the toxins that your body is losing. So even though there may not be any harmful effects, it definitely is sensible not to mix the acai berry drink mix and alcohol.