Aren't they supposed to be free of any side effects? Sugar free natura is one of the better substitutes out there and it is a good option for diabetes patients as well. But one of the main problems with these substitutes is that, it is much sweeter than normal sugar and little amounts are sufficient at a time. So you have to make sure that you don't add too much of sugar free natura. This contains fructose that had a very high sweet concentration. You must always tell everyone at home that they use should little at a time. Cheers!